A fixed-term postdoctoral research position is available for an outstanding individual in the research group of Dr. Michael Shaver at the School of Chemistry of the University of Edinburgh, United Kingdom. The successful candidate will use synthetic organic and polymer chemistry to prepare miRNA sensors as components of a hand-held, easy-to-use, sensitive device that can be used to assist with patient screening, early diagnosis and disease monitoring, with cancer diagnostics as an early target. The project builds upon recently obtained proof of concept data with collaborators in the School of Engineering and an industrial partner. The polymers in question respond rapidly to the presence of biological molecules, including microRNAs, which circulate within the blood and other bodily fluids. Such targets have been proven to be indicative of numerous disease and infection profiles. Although initially focussed upon chemical synthesis, future directions of the project will also include the printing of biosensing polymers onto disposable microelectrodes, and their electrical interrogation for point-of-care medical diagnosis applications. Due to the commercial sensitivity of the subject matter, further details of the project will be made available to candidates at the interview stage, under a non-disclosure agreement.
Applicants should have, or expect to receive by the start date, a PhD in synthetic organic chemistry, bioorganic chemistry, polymer science or a related field. Proven expertise in working with one or more of hydrogels, miRNA, PNA, bioconjugation or radical polymerisation is essential. They should be capable of working in an interdisciplinary team, leading other students where required. The applicant will join a dynamic team working on a MRC CiC funded project including Dr Phil Hands (School of Engineering) and a leading medical diagnostics industrial partner.
The position is available for an initial fixed-term of 12 months.
For more details and to apply:
Vacancy Reference: 033199