Morpholino Polymer Hydrogels as miRNA Sensors

Check our Gerry Langford’s new paper in ACS Sensors: It details our work in developing hydrogels with morpholino-based crosslinks that serve as sensors for single stranded oligonucelotide sequences. They show a remarkable improvement in sensitivity, salt tolerance, and temperature stability compared to ssDNA analogues and have detection limits as low as 10 pM. They even work using a simple mobile phone camera!

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Work with the GML, work with industry leader!

As part of our new transition to the University of Manchester, we are seeking an enthusiastic person to work with us and an industry leader in glass fibre insulation on a Knowledge Transfer Partnership (KTP) project. The ideal person will had a PhD in polymer synthesis or composites, with an expertise in sustainability a bonus. Above all, we are looking for an exceptional and independent learner, scientist and leader to undertake this 36-month project which has an overall aim of developing sustainable glass fibre insulation formulations.

The position will provide you with a unique opportunity to improve the sustainability of glass fibre insulation through their knowledge of polymer chemistry. Translating fundamental commodity polymer chemistry into the unique field of glass fibre composites will require a diverse knowledge of sustainability, composites, polymer chemistry, synthesis and characterisation. It will allow for the rapid development, pilot and scale-up of solutions to reduce the environmental footprint of a major construction product, making the process as “green” as possible whilst retaining or improving material performance. Understanding the applicability of potential solutions to fit with existing company infrastructure will provide ideal training as a transition to a career in the chemicals or polymers industries in the UK, but also extensive experiential learning in communication and leadership. This collaborative project will be directly connected to the training and development aspect of the KTP, with integration of both composites and sustainability training into the Associate’s role.

Based at the University of Manchester School of Materials and extensive travel to company premises, You will work directly with supervisors from both the University and the company and will use the facilities and resources of both organisations.

For more details check out:

https://www.jobs.manchester.ac.uk/

Or send Mike an email with any enquiries.

 

Topological Control from a Synthetic Polymer

Congrats to Mohammed Alkattan and our University of Glasgow collaborator Joelle Prunet who have just had a really cool paper accepted as a VIP article in Angewandte Chemie:

https://onlinelibrary.wiley.com/doi/abs/10.1002/ange.201805113

TOC Angw

The paper details our work on creating stereoregular cyclopolyethers. Ring-closing metathesis from an isotactic polyether affords the target cyclopolyether. Stereoselective cis-dihydroxylation gives a PEGose framework that mimics the helical ladder structure of amylose. This topological control of synthetic polymer frameworks is a really tough challenge in polymer science in the quest for biopolymer mimics. Great work!

Joseph Black Stars

Big congratulations to Meng Wang (2nd Place Talk Prize – Materials Chemistry) and Joanne Dunne (2nd Place Poster Prize – Synthesis and Catalysis) for their award winning work at the 4th annual Joseph Black Conference on 31 May.

Big congratulations to the rest of the group as well – Gerry gave a great talk in the Chem/Bio section on his sensor work; Dan and Mo both gave great talks in the Syn/Cat section (although Dan needs to get his face onto Titanium Man’s body, too…); and both Vishal and Yas had really attractive posters presenting their work on new polymers.

Great work!

One Last Lecture in Japan…

In my last week here in Japan, I presented a lecture to the local section of the Society of Polymer Science Japan, which has been promoting polymer science in industry and academia since 1951. Hosted by Prof. Masami Kamigaito, this was a fun lecture with lots of good questions from the students and staff attending, and an enjoyable meal of eel, a Nagoya specialty. I’m hopeful that Assistant Prof. Mineto Uchiyama keeps in touch – he just wouldn’t stop talking the entire night! Thanks very much for the hospitality – and hopefully we can collaborate in the future.IMG_4775.JPG

Science Adventures in Japan

My two months in Japan hosted by Nagoya University’s Research Center for Materials Science are almost at an end. I have thoroughly enjoyed my time here and have learned a lot, both about Japanese culture and the remarkable science going on here in Nagoya and the rest of Japan.

My principal host on this adventure is Prof. Kunio Awaga, whose work sits at the interface between coordination chemistry and materials science, has been an exceptional guide. Our many lunches and “tea-times” have been a welcome tether during my stay. I have also appreciated the opportunity to learn more about the rest of the exceptional science going on in Nagoya, including emerging collaborations with the groups of Prof. Susumu Saito and Prof. Shigehiro Yamaguchi which seem super interesting and impactful.

I’ve also had the opportunity to explore beyond Nagoya, with excellent experiences talking science with Prof. Mitsuo Sawamoto at Chubu University, Prof. Makoto Ouchi (and his excellent – and humorous – colleagues!) at Kyoto University and Assistant Prof. Yasuhiro Kohsaka at Shinshu University. Hopefully some super collaborations to come out of those trips as well, especially with Yasuhiro’s interesting monomer collection!

Thanks to everyone who has been an exceptional host during my time here in Japan – I’m very appreciative of the hospitality and looking forward to my next visit!