Guilhem obtained his B.S. in chemistry at California Polytechnic State University, San Luis Obispo CA. While there, he worked with Prof. Philip Costanzo on polymer surfactants, which included a yearlong internship at Sandia National Laboratories in Livermore, CA. He then went to the University of Minnesota and obtained his Ph.D. in Chemistry in the research group of Prof. Marc Hillmyer, focusing on the design and characterization of sustainable cross-linked plastics as well as their enzymatic degradation; the latter involved a long-term visit to work in the labs of Prof. Dr. Kris McNeill and Dr. Michael Sander at ETH Zurich in Switzerland. After obtaining his Ph.D., Guilhem did postdoctoral research on antifouling polymers with Prof. Matthew Tirrell, primarily at Argonne National Laboratory. Following this, Guilhem moved abroad to join the Shaver group as a research fellow working in the Sustainable Materials Innovation Hub at the University of Manchester.